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It is the only drug authorised by the EMA to treat the whole disease in adults, and by the FDA to treat patients who have cataplexy with the indication to be used for combating excessive daytime sleepiness. [4] [20] This drug helps to normalise sleep architecture and inhibits the intrusion REM sleep elements like paralysis during the day. [4]
A patient with depression and catalepsy Rigidity of the body produced by catalepsy. Symptoms include a rigid body, rigid limbs, limbs staying in same position when moved (waxy flexibility), no response, loss of muscle control, and slowing down of bodily functions, such as breathing.
Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. [1] The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1]
These night terrors can occur each night if the individual does not eat a proper diet, get the appropriate amount or quality of sleep (e.g., sleep apnea), well endure stressful events, and if they remain untreated. Adult night terrors are much less common and often respond to treatments to rectify causes of poor quality or quantity of sleep.
Person passed out on a sidewalk in New York City, 2008. In jurisprudence, unconsciousness may entitle the criminal defendant to the defense of automatism, i.e. a state without control of one's own actions, an excusing condition that allows a defendant to argue that they should not be held criminally liable for their actions or omissions.
Episodes of vasovagal syncope are typically recurrent and usually occur when the predisposed person is exposed to a specific trigger. Before losing consciousness, the individual frequently experiences early signs or symptoms such as lightheadedness, nausea, the feeling of being extremely hot or cold (accompanied by sweating), ringing in the ears, an uncomfortable feeling in the heart, fuzzy ...
The "feels like" temperature, generally, is a more accurate description of what the human body will experience when stepping outside. The "feels like" temperature, generally, is a more accurate ...
Orexin (/ ɒ ˈ r ɛ k s ɪ n /), also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. [5] It exists in the forms of orexin-A and orexin-B.The most common form of narcolepsy, type 1, in which the individual experiences brief losses of muscle tone ("drop attacks" or cataplexy), is caused by a lack of orexin in the brain due to destruction of the cells ...
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