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The formation of phenyl-hydroxy bromazolam was catalysed by CYP2B6, CYP2C19, and CYP3A4. 4-hydroxy bromazolam, as well as α-hydroxy bromazolam, were formed by CYP2B6, CYP2C19, CYP3A4, and CYP3A5. Additionally, CYP2C9 was found to catalyse the formation of α-hydroxy bromazolam as well. α-4-dihydroxy bromazolam was only found in incubations ...
The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses.
Bromazepam, sold under many brand names, is a benzodiazepine.It is mainly an anti-anxiety agent with similar side effects to diazepam.In addition to being used to treat anxiety or panic states, bromazepam may be used as a premedicant prior to minor surgery.
Chemical structure of alprazolam, a common triazolobenzodiazepine. Triazolobenzodiazepines (TBZD) are a class of benzodiazepine (BZD) derivative pharmaceutical drugs. . Chemically, they differ from other benzodiazepines by having an additional triazole ring fused to the dia
Flubromazolam (JYI-73) [2] [3] [4] is a triazolobenzodiazepine (TBZD), which are benzodiazepine (BZD) derivatives. [5] [6] [7] [8] [9] [10] [11] Flubromazolam is ...
Flurazepam [2] (marketed under the brand names Dalmane and Dalmadorm) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties.
It was invented in Japan, and this is the main country in which it has been used medically. It has sedative , muscle relaxant , anticonvulsant , and anxiolytic effects similar to those produced by other benzodiazepine derivatives, and though it is around the same potency as diazepam , it produces a more marked sedation and impaired coordination.
Felbamate (marketed under the brand name Felbatol by MedPointe) is an anticonvulsant [2] used in the treatment of epilepsy.It is used to treat partial seizures [3] [4] (with and without generalization) in adults and partial and generalized seizures associated with Lennox–Gastaut syndrome in children.