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Nitrous oxide is neurotoxic, and medium or long-term habitual consumption of significant quantities can cause neurological harm with the potential for permanent damage if left untreated. [104] [103] It is believed that, like other NMDA receptor antagonists, N 2 O produces Olney's lesions in rodents upon prolonged (several hour) exposure.
Long-term or habitual use can lead to severe neurological damage. [3] Nitrous oxide is said to enhance the effects of psychedelics. [6] Since nitrous oxide can cause dizziness, dissociation, and temporary loss of motor control, it is unsafe to inhale while standing up. Safer use can involve inhalation while seated to decrease risks of injury by ...
There are few side effects, other than vomiting, with short-term use. [1] [2] With long-term use anemia or numbness may occur. [2] It should always be given with at least 21% oxygen. [2] It is not recommended in people with a bowel obstruction or pneumothorax. [2] Use in the early part of pregnancy is not recommended. [1]
Nitrous oxide is thought to be particularly non-toxic, though heavy long-term use can lead to a variety of serious health problems linked to the destruction of vitamin B12 and folic acid. [17] [18] Nitrous oxide "whippets" are small aerosol containers designed for charging whipped cream dispensers.
Nitric Oxide Side Effects. GASTROINTESTINAL ISSUES, LIKE vomiting and diarrhea, are the most common side effects of nitric oxide supplements, Rothstein says.
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Other effects include diaphoresis, chest pain, and persistent dry cough, all of which may result in weight loss, anorexia and may also lead to right-side heart enlargement and heart disease in advanced cases. Prolonged exposure to relatively low levels of nitrogen (II) oxide may cause persistent headaches and nausea. [18]
Inhalation sedation using nitrous oxide has a long history of safe use in both medicine and dentistry. It can therefore be used safely in most patients in the dental setting. [5] However, in some patients sedation with nitrous oxide would be unsuitable. Some examples are below. A patient who is unable to use a nasal mask.