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Molecular imprinting is a technique to create template-shaped cavities in polymer matrices with predetermined selectivity and high affinity. [1] This technique is based on the system used by enzymes for substrate recognition, which is called the "lock and key" model.
A lock and key is a pair of devices used to secure an object or location from unauthorized access. Lock and Key or Lock & Key may also refer to: Arts, entertainment, and media
In 1907, he received the Nobel Prize in Chemistry for "his discovery of cell-free fermentation". Following Buchner's example, enzymes are usually named according to the reaction they carry out: the suffix -ase is combined with the name of the substrate (e.g., lactase is the enzyme that cleaves lactose ) or to the type of reaction (e.g., DNA ...
The induced fit model is a development of the lock-and-key model and assumes that an active site is flexible and changes shape until the substrate is completely bound. This model is similar to a person wearing a glove: the glove changes shape to fit the hand. The enzyme initially has a conformation that attracts its substrate.
The locks-and-keys approach represents pointers as ordered pairs (key, address) where the key is an integer value. Heap-dynamic variables are represented as the storage for the variable plus a cell for an integer lock value. When a variable is allocated, a lock value is created and placed both into the variable's cell and into the pointer's key ...
Using the "lock and key model" of enzyme binding, a drug (key) must be of roughly the proper dimensions to fit the enzyme's binding site (lock). [28] Using the appropriately sized molecular scaffold, drugs must also interact with the enzyme non-covalently in order to maximize binding affinity binding constant and reduce the ability of the drug ...
A tubular lock and key. A tubular pin tumbler lock, also known as a circle pin tumbler lock, radial lock, or the trademark Ace lock popularized by manufacturer Chicago Lock Company since 1933, is a variety of pin tumbler lock in which a number of pins are arranged in a circular pattern, and the corresponding key is tubular or cylindrical in shape.
While observing the lock, the attacker manipulates the dial to align the lock gates so that the fence falls and the bolt is disengaged. Bypass attacks involve physical manipulation of both the lock and its bolt mechanism. Punching, peeling and using a torch are other methods of compromising a safe.