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  2. Bimekizumab - Wikipedia

    en.wikipedia.org/wiki/Bimekizumab

    Bimekizumab, sold under the brand name Bimzelx (/ b ɪ m ˈ z ɛ l ɪ k s / bim-ZEL-iks), is a humanized anti-IL17A, anti-IL-17F, and anti-IL17AF monoclonal antibody [6] [7] that is used to treat plaque psoriasis, psoriatic arthritis, axial spondyloarthritis, ankylosing spondylitis, and hidradenitis suppurativa.

  3. Secukinumab - Wikipedia

    en.wikipedia.org/wiki/Secukinumab

    Secukinumab inhibits a member of the cytokine family, interleukin 17A, which is produced mainly by inflammatory T helper 17 cells. [11] IL17A is upregulated in serum of people with psoriasis and in the synovial fluid of people with psoriatic arthritis, and promotes inflammation when it binds to the interleukin-17 receptor which is expressed in various types of cells, including keratinocytes in ...

  4. Psoriatic erythroderma - Wikipedia

    en.wikipedia.org/wiki/Psoriatic_erythroderma

    The US Food and Drug Administration has approved cyclosporine for the management of severe plaque psoriasis in immunocompetent individuals. [27] Cyclosporine is regarded as an essential first-line medication for the management of unstable cases of psoriatic erythroderma because of its quick onset of action. [23]

  5. Risankizumab - Wikipedia

    en.wikipedia.org/wiki/Risankizumab

    Risankizumab, sold under the brand name Skyrizi (/ s k aɪ ˈ r ɪ z i / sky-RIZZ-ee), is a humanized monoclonal antibody used for the treatment of plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis. [6] [7] It is designed to target interleukin 23A (IL-23A). [6] [7] [9] It is given by subcutaneous injection. [6] [7]

  6. Etanercept - Wikipedia

    en.wikipedia.org/wiki/Etanercept

    It has US Food and Drug Administration (FDA) approval to treat rheumatoid arthritis, juvenile idiopathic arthritis and psoriatic arthritis, plaque psoriasis and ankylosing spondylitis. Tumor necrosis factor alpha (TNFα) is the "master regulator" of the inflammatory (immune) response in many organ systems. Autoimmune diseases are caused by an ...

  7. Adalimumab - Wikipedia

    en.wikipedia.org/wiki/Adalimumab

    Adalimumab, sold under the brand name Humira and others, is a disease-modifying antirheumatic drug and monoclonal antibody used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, and uveitis.

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