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Bullous impetigo is a bacterial skin infection caused by Staphylococcus aureus that results in the formation of large blisters called bullae, usually in areas with skin folds like the armpit, groin, between the fingers or toes, beneath the breast, and between the buttocks.
Treatment: If you suspect you have impetigo, pay a visit to your primary healthcare provider. They may prescribe topical or oral antibiotics, per the CDC . Siro Rodenas Cortes - Getty Images
Impetigo is a contagious bacterial infection that involves the superficial skin. [2] The most common presentation is yellowish crusts on the face, arms, or legs. [ 2 ] Less commonly there may be large blisters which affect the groin or armpits . [ 2 ]
[15] [16] Nonbullous impetigo is the most common form, representing approximately 70% of diagnosed cases. [15] The remaining 30% of cases represent bullous form, which is primarily caused by S. aureus. [15] [17] In rare instances, bullous impetigo can spread and lead to Staphylococcal Scalded Skin Syndrome (SSSS), a potentially life-threatening ...
The treatment of choice is penicillin, and the duration of treatment is around 10 days. [23] Antibiotic therapy (using injected penicillin) has been shown to reduce the risk of acute rheumatic fever. [24] In individuals with a penicillin allergy, erythromycin, other macrolides, and cephalosporins have been shown to be effective treatments. [25]
A 2010 (updated in 2023) meta-analysis of 14 randomized controlled trials showed that oral steroids and potent topical steroids are effective treatments, although their use may be limited by side-effects, while lower doses of topical steroids are safe and effective for treatment of moderate bullous pemphigoid.
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SSSS is a clinical diagnosis. This is sometimes confirmed by isolation of S. aureus from blood, mucous membranes, or skin biopsy; however, these are often negative. Skin biopsy may show separation of the superficial layer of the epidermis (intraepidermal separation), differentiating SSSS from TEN, wherein the separation occurs at the dermo-epidermal junction (subepidermal separation).