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These side effects are serious and some of them are permanent, and many remain a crucial concern for companies and healthcare professionals and substantial efforts are being encouraged to reduce the potential risks for future antipsychotics through more clinical trials and drug development.
Common adverse effects of olanzapine, occurring from 1–10%, include: Gynecomastia [8] Extrapyramidal symptoms (EPS) (dose-dependent). Tends to produce less extrapyramidal side effects than typical antipsychotics but more extrapyramidal side effects than sertindole, clozapine and quetiapine. [9] [10]
Neuroleptic malignant syndrome (NMS) is a rare [5] [6] but life-threatening reaction that can occur in response to antipsychotics (neuroleptic) or other drugs that block the effects of dopamine. [1] [7] Symptoms include high fever, confusion, rigid muscles, variable blood pressure, sweating, and fast heart rate. [1]
Serious side effects may include movement disorders including tardive dyskinesia and neuroleptic malignant syndrome. [6] Use in pregnancy and breastfeeding is generally not recommended. [ 10 ] It is a typical antipsychotic which is believed to work by reducing the action of dopamine in the brain.
This is a list of adverse effects of risperidone. Risperidone , sold under the brand name Risperdal among others, is an antipsychotic . [ 1 ] It is used to treat schizophrenia , bipolar disorder , and irritability associated with autism .
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Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.
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