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  2. Syphilis - Wikipedia

    en.wikipedia.org/wiki/Syphilis

    Most new cases in the United States (60%) occur in men who have sex with men; and in this population 20% of syphilis cases were due to oral sex alone. [3] [36] Syphilis can be transmitted by blood products, but the risk is low due to screening of donated blood in many countries. [3] The risk of transmission from sharing needles appears to be ...

  3. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Pfizer originally discovered the medication in 1989 while looking for a treatment for angina. [11] It was approved for medical use in the United States and in the European Union in 1998. [ 5 ] [ 8 ] [ 11 ] [ 12 ] In 2022, it was the 157th most commonly prescribed medication in the United States, with more than 3 million prescriptions.

  4. Treponema pallidum - Wikipedia

    en.wikipedia.org/wiki/Treponema_pallidum

    [68] [69] [70] The outer membrane of T. pallidum has too few surface proteins for an antibody to be effective. Efforts to develop a safe and effective syphilis vaccine have been hindered by uncertainty about the relative importance of humoral and cellular mechanisms to protective immunity, [ 71 ] and because T. pallidum outer membrane proteins ...

  5. With cases rising, FDA authorizes first over-the-counter home ...

    www.aol.com/cases-rising-fda-authorizes-first...

    In 2022, there were more than 207,000 total syphilis cases reported, the highest number since the 1950s, according to the CDC. Syphilis is a bacterial infection that may appear minor at first. In ...

  6. Sudden syphilis retreat in gay men is most likely tied to ...

    www.aol.com/sudden-syphilis-retreat-gay-men...

    The decline was driven by a 13% drop in such syphilis diagnoses among gay and bisexual men, who are about 2% of the adult population but have historically accounted for nearly half of such cases.

  7. FDA approves over-the-counter syphilis test amid national and ...

    www.aol.com/news/fda-approves-over-counter...

    Aug. 20—Amid a local and national surge of syphilis, the U.S. Food and Drug Administration this month approved an over-the-counter test for the sexually transmitted infection. While some may ...

  8. Arsphenamine - Wikipedia

    en.wikipedia.org/wiki/Arsphenamine

    Arsphenamine was used to treat the disease syphilis because it is toxic to the bacterium Treponema pallidum, a spirochete that causes syphilis. [6] Arsphenamine was originally called "606" because it was the sixth in the sixth group of compounds synthesized for testing; it was marketed by Hoechst AG under the trade name "Salvarsan" in 1910.

  9. Syphilis cases soar to highest level in 70 years - AOL

    www.aol.com/syphilis-cases-soar-highest-level...

    A staggering 207,000 syphilis cases were reported in the US in 2022 — an 80% increase since 2018. Syphilis cases soar to highest level in 70 years — CDC sounds alarm over ‘unacceptable’ crisis

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