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Aug. 20—Amid a local and national surge of syphilis, the U.S. Food and Drug Administration this month approved an over-the-counter test for the sexually transmitted infection. While some may ...
In 2022, there were more than 207,000 total syphilis cases reported, the highest number since the 1950s, according to the CDC. Syphilis is a bacterial infection that may appear minor at first. In ...
Most new cases in the United States (60%) occur in men who have sex with men; and in this population 20% of syphilis cases were due to oral sex alone. [3] [36] Syphilis can be transmitted by blood products, but the risk is low due to screening of donated blood in many countries. [3] The risk of transmission from sharing needles appears to be ...
Arsphenamine was used to treat the disease syphilis because it is toxic to the bacterium Treponema pallidum, a spirochete that causes syphilis. [6] Arsphenamine was originally called "606" because it was the sixth in the sixth group of compounds synthesized for testing; it was marketed by Hoechst AG under the trade name "Salvarsan" in 1910.
[68] [69] [70] The outer membrane of T. pallidum has too few surface proteins for an antibody to be effective. Efforts to develop a safe and effective syphilis vaccine have been hindered by uncertainty about the relative importance of humoral and cellular mechanisms to protective immunity, [ 71 ] and because T. pallidum outer membrane proteins ...
A staggering 207,000 syphilis cases were reported in the US in 2022 — an 80% increase since 2018. Syphilis cases soar to highest level in 70 years — CDC sounds alarm over ‘unacceptable’ crisis
In the United States rates of syphilis have increased among men between 2000 and 2007. [19] Rates are six times greater in men than women and seven times greater in African Americans than Caucasians. [19] More than 60% of cases are in men who have sex with men. [19] It occurs most commonly in those between 15 and 40 years of age. [20]
The decline was driven by a 13% drop in such syphilis diagnoses among gay and bisexual men, who are about 2% of the adult population but have historically accounted for nearly half of such cases.