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The EMBL Nucleotide Sequence Database (EMBL-Bank) has increased in size from around 600 entries in 1982 to over 2.5×10 8 by December 2012. [16] The EMBL Nucleotide Sequence Database (also known as EMBL-Bank) is the section of the ENA which contains high-level genome assembly details, as well as assembled sequences and their functional annotation.
The International Nucleotide Sequence Database Collaboration (INSDC) consists of a joint effort to collect and disseminate databases containing DNA and RNA sequences. [1] It involves the following computerized databases: NIG's DNA Data Bank of Japan (), NCBI's GenBank and the EMBL-EBI's European Nucleotide Archive ().
3D structure protein databases, Protein sequence databases MobiDB: Database of intrinsically disordered and mobile proteins: John Moult, Christine Orengo, Predrag Radivojac University of Padua: Italian Government database of intrinsic protein disorder annotation 3D structure protein databases, Protein sequence databases ModBase
Each EMBL site has a specific research field. The EMBL-EBI is a hub for bioinformatics research and services, developing and maintaining a large number of scientific databases that are free of charge. At Grenoble and Hamburg, research is focused on structural biology. EMBL Rome. The EMBL Rome site is dedicated to the study of epigenetics and ...
The European Bioinformatics Institute (EMBL-EBI) is an intergovernmental organization (IGO) which, as part of the European Molecular Biology Laboratory (EMBL) family, focuses on research and services in bioinformatics. It is located on the Wellcome Genome Campus in Hinxton near Cambridge, and employs over 600 full-time equivalent (FTE) staff. [4]
The GenBank sequence database is an open access, annotated collection of all publicly available nucleotide sequences and their protein translations. It is produced and maintained by the National Center for Biotechnology Information (NCBI; a part of the National Institutes of Health in the United States) as part of the International Nucleotide Sequence Database Collaboration (INSDC).
NCBI had responsibility for making available the GenBank DNA sequence database since 1992. [4] GenBank coordinates with individual laboratories and other sequence databases, such as those of the European Molecular Biology Laboratory (EMBL) and the DNA Data Bank of Japan (DDBJ).
UniRef100 sequences are clustered using the CD-HIT algorithm to build UniRef90 and UniRef50. [20] [21] Each cluster is composed of sequences that have at least 90% or 50% sequence identity, respectively, to the longest sequence. Clustering sequences significantly reduces database size, enabling faster sequence searches.