Search results
Results from the WOW.Com Content Network
Spindle cell sarcoma in muscle tissue Spindle cell sarcoma is a type of connective tissue cancer . The tumors generally begin in layers of connective tissue , as found under the skin, between muscles, and surrounding organs, and will generally start as a small, inflamed lump, which grows in size.
Warburg regarded the fundamental difference between normal and cancerous cells to be the ratio of glycolysis to respiration; this observation is also known as the Warburg effect. In the somatic mutation theory of cancer, malignant proliferation is caused by mutations and altered gene expression, in a process called malignant transformation ...
The primary Schwann cell differentiation and neoplastic proliferations are characteristics of peripheral nerve sheath tumors. For instance, the Schwann cell, which is the major neoplastic cell component of neurofibroma, [ 7 ] is cytologically distinguished by the expression of S-100 protein and wavy nuclear outlines.
Research supports that compression of tumor vessels by surrounding tumor cells results in mechanical tension and changes in blood flow. [8] It has been suggested that these flow-mediated changes cause abnormal expression of transcription factors which promotes aberrant endothelial morphology, size, and differentiation. [9]
A sarcoma is a malignant tumor, a type of cancer that arises from cells of mesenchymal (connective tissue) origin. [1] [2] Connective tissue is a broad term that includes bone, cartilage, muscle, fat, vascular, or other structural tissues, and sarcomas can arise in any of these types of tissues.
Spinal nerve compression and weakening of the vertebral structure cause the symptoms. Pain is the most common symptom at presentation. [ 1 ] [ 3 ] [ 7 ] Other common symptoms of spinal cord compression include muscle weakness, sensory loss , numbness in hands and legs, and rapid onset paralysis .
Spindle cell carcinoma is a type of cancer that begins in the skin or in tissues that line or cover internal organs and that contains long spindle-shaped cells. It is also called sarcomatoid carcinoma .
The cancer stem cell hypothesis proposes that the different kinds of cells in a heterogeneous tumor arise from a single cell, termed Cancer Stem Cell. Cancer stem cells may arise from transformation of adult stem cells or differentiated cells within a body. These cells persist as a subcomponent of the tumor and retain key stem cell properties.