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Tinidazole, sold under the brand name Tindamax among others, is a medication used against protozoan infections.It is widely known throughout Europe and the developing world as a treatment for a variety of anaerobic amoebic and bacterial infections.
The 5-nitroimidazole drugs (metronidazole and tinidazole) are the mainstay of treatment for infection with Trichomonas vaginalis. Treatment for both the infected patient and the patient's sexual partner is recommended, even if asymptomatic. Therapy other than 5-nitroimidazole drugs is also an option, but cure rates are much lower. [25]
In those with Giardia species or Entamoeba histolytica, tinidazole treatment is recommended and superior to metronidazole. [ 36 ] [ 76 ] The World Health Organization (WHO) recommends the use of antibiotics in young children who have both bloody diarrhea and fever.
Electrolyte solutions, while not true antidiarrheals, are used to replace lost fluids and salts in acute cases.; Bulking agents like methylcellulose, guar gum or plant fibre (bran, sterculia, isabgol, etc.) are used for diarrhoea in functional bowel disease and to control ileostomy output.
In places where infections are not common, it is a second line treatment after paromomycin when a person has no symptoms. [2] For people who are symptomatic, it is used after treatment with metronidazole or tinidazole. [2] It is taken by mouth. [1] Diloxanide generally has mild side effects. [3]
Asymptomatic cases often do not need treatment. [1] When symptoms are present, treatment is typically provided with either tinidazole or metronidazole. [1] Infection may cause a person to become lactose intolerant, so it is recommended to temporarily avoid lactose following an infection. [1] Resistance to treatment may occur in some patients. [1]
Metronidazole, or a related drug such as tinidazole, secnidazole or ornidazole, is used to destroy amoebae that have invaded tissue. [2] These are rapidly absorbed into the bloodstream and transported to the site of infection. Because they are rapidly absorbed there is almost none remaining in the intestine.
Antiprotozoal agents (ATC code: ATC P01) is a class of pharmaceuticals used in treatment of protozoan infection. A paraphyletic group , protozoans have little in common with each other. For example, Entamoeba histolytica , a unikont eukaryotic organism, is more closely related to Homo sapiens (humans), which also belongs to the unikont ...