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Importantly, 82 Rb PET also seems to provide prognostic value in patients who are obese and whose diagnosis remains uncertain after SPECT-MPI. 82 Rb myocardial blood flow quantification is expected to improve the detection of multivessel coronary heart disease. [9] 82 Rb/PET is a valuable tool in ischemia identification. Myocardial Ischemia is ...
It is rapidly taken up by heart muscle cells, and therefore can be used to identify regions of heart muscle that are receiving poor blood flow in a technique called PET perfusion imaging. [2] The half-life of rubidium-82 is only 1.27 minutes; it is normally produced at the place of use by rubidium generators. [3]
Cardiac PET (or cardiac positron emission tomography) is a form of diagnostic imaging in which the presence of heart disease is evaluated using a PET scanner. Intravenous injection of a radiotracer is performed as part of the scan. Commonly used radiotracers are Rubidium-82, Nitrogen-13 ammonia and Oxygen-15 water. [1]
This limitation restricts clinical PET primarily to the use of tracers labelled with fluorine-18, which has a half-life of 110 minutes and can be transported a reasonable distance before use, or to rubidium-82 (used as rubidium-82 chloride) with a half-life of 1.27 minutes, which is created in a portable generator and is used for myocardial ...
Other than 87 Rb, the longest-lived radioisotopes are 83 Rb with a half-life of 86.2 days, 84 Rb with a half-life of 33.1 days, and 86 Rb with a half-life of 18.642 days. All other radioisotopes have half-lives less than a day. 82 Rb is used in some cardiac positron emission tomography scans to assess myocardial perfusion. It has a half-life of ...
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Myocardial perfusion imaging or scanning (also referred to as MPI or MPS) is a nuclear medicine procedure that illustrates the function of the heart muscle (). [1]It evaluates many heart conditions, such as coronary artery disease (CAD), [2] hypertrophic cardiomyopathy and heart wall motion abnormalities.
Cardiac stress testing is used to determine to assess cardiac function and to disclose evidence of exertion-related cardiac hypoxia. Radionuclide testing using thallium or technetium can be used to demonstrate areas of perfusion abnormalities. With a maximal stress test the level of exercise is increased until the person's heart rate will not ...