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Hydroxyapatite (IMA name: hydroxylapatite [5]) (Hap, HAp, or HA) is a naturally occurring mineral form of calcium apatite with the formula Ca 5 (PO 4) 3 (OH), often written Ca 10 (PO 4) 6 (OH) 2 to denote that the crystal unit cell comprises two entities. [6] It is the hydroxyl endmember of the complex apatite group.
Through use of a phase diagram, Hench chose a composition of 45% , 24.5% , 24.5% , and 6% to allow for a large amount of and some in a matrix. [5] The glass was batched, melted, and cast into small rectangular implants to be inserted into the femoral bone of rats for six weeks as developed by Dr. Ted Greenlee of the University of Florida. [ 5 ]
The human body is composed of approximately: 64% water, 20% protein, 10% fat, 1% carbohydrate, 5% minerals. [1] The decomposition of soft tissue is characterized by the breakdown of these macromolecules, and thus a large proportion of the decomposition products should reflect the amount of protein and fat content initially present in the body. [4]
Apatite is a group of phosphate minerals, usually hydroxyapatite, fluorapatite and chlorapatite, with high concentrations of OH −, F − and Cl − ion, respectively, in the crystal. The formula of the admixture of the three most common endmembers is written as Ca 10 ( PO 4 ) 6 (OH,F,Cl) 2 , and the crystal unit cell formulae of the ...
Calcium hydroxyphosphate (calcium phosphate tribasic, tribasic calcium phosphate, hydroxyapatite, HAp) is an inorganic chemical compound that is made up of calcium, hydrogen, oxygen and phosphorus. Its formula is Ca 5 (OH)(PO 4) 3. [1] It is found in the body and as the mineral hydroxyapatite. [citation needed]
The first 5 steps are related to the Bioglass response to the environment within the body, and occur rapidly at the material surface over several hours. [17] Reaction steps 6–10 detail the reaction of the body to the integration of the biomaterial, and the process of integration with bone.
Phosphate minerals are minerals that contain the tetrahedrally coordinated phosphate (PO 3− 4) anion, sometimes with arsenate (AsO 3− 4) and vanadate (VO 3− 4) substitutions, along with chloride (Cl −), fluoride (F −), and hydroxide (OH −) anions, that also fit into the crystal structure.
The following chart shows the solubility of various ionic compounds in water at 1 atm pressure and room temperature (approx. 25 °C, 298.15 K). "Soluble" means the ionic compound doesn't precipitate, while "slightly soluble" and "insoluble" mean that a solid will precipitate; "slightly soluble" compounds like calcium sulfate may require heat to precipitate.