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  2. Apremilast - Wikipedia

    en.wikipedia.org/wiki/Apremilast

    Apremilast, sold under the brand name Otezla among others, is a medication for the treatment of certain types of psoriasis and psoriatic arthritis. [4] The drug acts as a selective inhibitor of the enzyme phosphodiesterase 4 (PDE4). [ 4 ]

  3. Amgen Reports Results From Otezla’s Phase 3 Trial For ... - AOL

    www.aol.com/news/amgen-reports-results-otezla...

    Amgen presented results from the Phase 3 ADVANCE trial of Otezla in patients with plaque psoriasis at the American Academy of Dermatology Virtual Meeting Experience 2021. In the placebo-controlled ...

  4. Race to Effective Psoriasis Treatment: Can-Fite's ... - AOL

    www.aol.com/news/race-effective-psoriasis...

    Amgen Inc. (NASDAQ: AMGN) recently announced that the U.S. Food and Drug Administration (FDA) has accepted for review the supplemental New Drug Application (sNDA) for Otezla for the treatment of ...

  5. PDE4 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE4_inhibitor

    Crisaborole (AN2728), a boron-containing drug for the topical treatment of psoriasis and atopic dermatitis. [24] [25] It was approved by the FDA on December 14, 2016 under the brand name Eucrisa for the treatment of mild-to-moderate atopic dermatitis (eczema) in patients 2 years of age and older. [26] Caffeine is a weak, non-selective PDE ...

  6. The Dow Jones Industrials Are Winning 2025: 4 Highest ... - AOL

    www.aol.com/dow-jones-industrials-winning-2025...

    Otezla for the treatment of adult patients with plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behcet's disease Aranesp to treat a lower-than-normal number of red blood ...

  7. Amgen - Wikipedia

    en.wikipedia.org/wiki/Amgen

    The FDA also approved Amgen's Otezla for adults with plaque psoriasis of any severity level. [106] 2022: In January, Amgen announced a research collaboration with Generate Biomedicines across multiple modalities and several therapeutic areas for up to $1.9 billion.

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