Search results
Results from the WOW.Com Content Network
Early in meiosis 1, Ime2 activity rises and is required for the normal accumulation and activity of Ndt80. However, if Ndt80 is expressed prematurely, it will initially accumulate in an unmodified form. Ime2 can then also act as a meiosis-specific kinase that phosphorylates Ndt80, resulting in fully activated Ndt80. [26]
Crossing over occurs between prophase I and metaphase I and is the process where two homologous non-sister chromatids pair up with each other and exchange different segments of genetic material to form two recombinant chromosome sister chromatids. It can also happen during mitotic division, [1] which may
Most recombination occurs naturally and can be classified into two types: (1) interchromosomal recombination, occurring through independent assortment of alleles whose loci are on different but homologous chromosomes (random orientation of pairs of homologous chromosomes in meiosis I); & (2) intrachromosomal recombination, occurring through ...
The X chromosome carries hundreds of genes but few, if any, of these have anything to do directly with sex determination. Early in embryonic development in females, one of the two X chromosomes is permanently inactivated in nearly all somatic cells (cells other than egg and sperm cells).
Spo11 is a protein that in humans is encoded by the SPO11 gene.Spo11, in a complex with mTopVIB, creates double strand breaks to initiate meiotic recombination. [5] [6] Its active site contains a tyrosine which ligates and dissociates with DNA to promote break formation.
9156 26909 Ensembl ENSG00000174371 ENSMUSG00000039748 UniProt Q9UQ84 Q5T397 Q9QZ11 RefSeq (mRNA) NM_003686 NM_006027 NM_130398 NM_001319224 NM_012012 RefSeq (protein) NP_001306153 NP_003677 NP_006018 NP_569082 NP_036142 Location (UCSC) Chr 1: 241.85 – 241.9 Mb Chr 1: 175.71 – 175.74 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Exonuclease 1 is an enzyme that in humans is ...
During meiosis, homologous recombination can produce new combinations of genes as shown here between similar but not identical copies of human chromosome 1. Homologous recombination is a type of genetic recombination in which genetic information is exchanged between two similar or identical molecules of double-stranded or single-stranded ...
Mechanically, the process is similar to mitosis, though its genetic results are fundamentally different. The result is the production of four haploid cells (n chromosomes; 23 in humans) from the two haploid cells (with n chromosomes, each consisting of two sister chromatids) [clarification needed] produced in meiosis I. The four main steps of ...