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Tissue hypoxia refers to low levels of oxygen in the tissues of the body and the term hypoxia is a general term for low levels of oxygen. [2] Hypoxemia is usually caused by pulmonary disease whereas tissue oxygenation requires additionally adequate circulation of blood and perfusion of tissue to meet metabolic demands. [4]
Hypoxia differs from hypoxemia and anoxemia, in that hypoxia refers to a state in which oxygen present in a tissue or the whole body is insufficient, whereas hypoxemia and anoxemia refer specifically to states that have low or no oxygen in the blood. [3] Hypoxia in which there is complete absence of oxygen supply is referred to as anoxia.
Intraalveolar blood vessels (pulmonary capillaries) are thin walled vessels adjacent to alveoli which are subject to the pressure changes described by zones 1-3. Flow in zone 4 is governed by the arteriointerstitial pressure difference (Pa − Pi). This is because as Pi rises, the arterial caliber is reduced, thereby increasing resistance to flow.
The exaerobic zone is found at the boundary of anoxic and hypoxic zones. Hypoxia can occur throughout the water column and also at high altitudes as well as near sediments on the bottom. It usually extends throughout 20–50% of the water column, but depends on the water depth and location of pycnoclines (rapid changes in water density with depth).
For this reason, some climbers carry supplemental oxygen to prevent hypoxia, edema, and HAPE. The standard drug treatment of dexamethasone does not alter the hypoxia or the consequent vasoconstriction, but stimulates fluid reabsorption in the lungs to reverse the edema. Additionally, several studies on native populations remaining at high ...
Permanent dead zones are deep water occurrences that rarely exceed 2 milligrams per liter. Temporary dead zones are short lived dead zones lasting hours or days. Seasonal dead zones are annually occurring, typically in warm months of summer and autumn. Diel cycling hypoxia is a specific seasonal dead zone that only becomes hypoxic during the night
An SaO 2 (arterial oxygen saturation) value below 90% causes hypoxia (which can also be caused by anemia). Hypoxia due to low SaO 2 is indicated by cyanosis, but oxygen saturation does not directly reflect tissue oxygenation. The affinity of hemoglobin to oxygen may impair or enhance oxygen release at the tissue level.
Histotoxic hypoxia, the inability of cells to take up or use oxygen from the bloodstream; Anemic hypoxia, Blood is not able to take sufficient amount of oxygen due to Anemia; Hypoxemic hypoxia or hypoxemia, a deficiency of oxygen in arterial blood; Hypoxic hypoxia, a result of insufficient oxygen available to the lungs