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Inositol has been used as an adulterant or cutting agent for many illegal drugs, such as cocaine, methamphetamine, and sometimes heroin, [47] probably because of its solubility, powdery texture, or reduced sweetness (50%) compared to more common sugars. Inositol is also used as a stand-in film prop for cocaine in filmmaking. [48] [49]
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The chemical compound 1L-chiro-inositol [2] (often called L-chiro-inositol or LCI) is one of the nine stereoisomers of cyclohexane-1,2,3,4,5,6-hexol, with formula C 6 H 12 O 6, the generic "inositol". Its molecule has a ring of six carbon atoms, each bonded to a hydrogen atom and a hydroxyl group (–OH). Imagining the ring is horizontal, the ...
D-chiro-inositol is known to be an important secondary messenger in insulin signal transduction.It accelerates the dephosphorylation of glycogen synthase and pyruvate dehydrogenase, rate limiting enzymes of non-oxidative and oxidative glucose disposal.
Inositol nicotinate, also known as inositol hexanicotinate or inositol hexaniacinate, is a compound of niacin (vitamin B3) and inositol. It is marketed in the United States as a "no-flush" form of niacin in dietary supplements.
The designation rac-chiro-inositol has been used for the racemic mixture (racemate) of equal parts of the two chiro isomers. It crystallizes as a single phase, rather than separate D and L crystals, that melts at 250 °C (which is 4–5 °C higher than the melting point of the pure enantiomers) and decomposes between 308 and 344 °C.
Inositol hexaphosphate (IP6) is the most abundant inositol phosphate isomer found. IP6 is solely involved in various biological activities such as neurotransmission, immune response, regulation of kinase and phosphatase proteins as well as activation of calcium channels.
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