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MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is an organic compound. It is classified as a tetrahydropyridine . It is of interest as a precursor to the monoaminergic neurotoxin MPP + , which causes permanent symptoms of Parkinson's disease by destroying dopaminergic neurons in the substantia nigra of the brain .
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes permanent symptoms of Parkinson's disease. (–)-Mitragynine is a naturally occurring tetrahydropyridine. 2,3,4,5-Tetrahydropyridine, a colorless liquid, is commercially available. It is an imine. Illustrating another isomer of tetrahydropyridine, 6-acetyl-2,3,4,5-tetrahydropyridine occurs ...
The 3 substrates of this enzyme are succinyl-CoA, (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate, and H 2 O, whereas its two products are CoA and N-succinyl-L-2-amino-6-oxoheptanedioate. This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name ...
The Hinduhridaysamrat Balasaheb Thackeray Medical College, also known as HBT Medical College, is a public medical college located in Juhu, Mumbai, India. [2] It is owned and operated by the Brihanmumbai Municipal Corporation. The medical college is attached with Dr. R.N. Cooper Municipal General Hospital. [3]
Methylphenyltetrahydropyridine N-monooxygenase (EC 1.13.12.11) is an enzyme with systematic name 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase. [1] This enzyme catalyses the following chemical reaction
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Hinduja Hospital, Mahim, is a not-for-profit institution, with at least 20% of its total capacity reserved for people from the economically weaker section. It has committed 10% of its total beds for subsidised / concessional treatments, and 10% beds for completely free treatments. [19] [20] [21]
Terpyridine is a tridentate ligand that binds metals at three meridional sites giving two adjacent 5-membered MN 2 C 2 chelate rings. [6] Terpyridine forms complexes with most transition metal ion as do other polypyridine compounds, such as 2,2'-bipyridine and 1,10-phenanthroline. Complexes containing two terpyridine complexes, i.e. [M(Terpy) 2 ...