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There are two distinctive mapping approaches used in the field of genome mapping: genetic maps (also known as linkage maps) [7] and physical maps. [3] While both maps are a collection of genetic markers and gene loci, [8] genetic maps' distances are based on the genetic linkage information, while physical maps use actual physical distances usually measured in number of base pairs.
FlyBase is an online bioinformatics database and the primary repository of genetic and molecular data for the insect family Drosophilidae. [1] For the most extensively studied species and model organism, Drosophila melanogaster, a wide range of data are presented in different formats.
Thomas Hunt Morgan's Drosophila melanogaster genetic linkage map. This was the first successful gene mapping work and provides important evidence for the chromosome theory of inheritance. The map shows the relative positions of allelic characteristics on the second Drosophila chromosome.
Crumbs homolog 1 is a protein that in humans is encoded by the CRB1 gene. [5] [6] [7]This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors.
Efforts in genome sequencing have allowed researchers to examine eusocial insect behavior from a molecular perspective. Notable progress in this field was made by the Honey Bee Genome Sequencing Consortium , led by Gene E. Robinson , which published and made public a completed honey bee ( Apis mellifera ) genome in October 2006. [ 2 ]
A brainbow of mouse neurons from Smith, 2007. Brainbow was initially developed by Jeff W. Lichtman and Joshua R. Sanes at Washington University in St. Louis. [1] The team constructed Brainbow using a two-step process: first, a specific genetic construct was generated that could be recombined in multiple arrangements to produce one of either three or four colors based on the particular ...
The map shows shows the relative positions of allelic characteristics on the second Drosophila chromosome. The distance between the genes (map units) are equal to the percentage of crossing-over events that occurs between different alleles. Reason High quality, scalable vector diagram of a classic and important scientific result
The most practiced method used thus far to insert transgenes into the Drosophila genome utilizes P elements. The transposable P elements, also known as transposons, are segments of bacterial DNA that are translocated into the genome, without the presence of a complementary sequence in the host's genome. P elements are administered in pairs of ...