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  2. Radiologically isolated syndrome - Wikipedia

    en.wikipedia.org/wiki/Radiologically_isolated...

    The most common reason for an initial MRI in these children was a headache. The first occurrence of a clinical event characteristic of MS in nearly half of the children examined was 2 years, though in a majority of cases, 'radiologic evolution', i.e. the increase in the number of size of lesions as detected in subsequent MRI, developed after ...

  3. Sturge–Weber syndrome - Wikipedia

    en.wikipedia.org/wiki/Sturge–Weber_syndrome

    Sturge–Weber syndrome, sometimes referred to as encephalotrigeminal angiomatosis, is a rare congenital neurological and skin disorder. It is one of the phakomatoses and is often associated with port-wine stains of the face, glaucoma, seizures, intellectual disability, and ipsilateral leptomeningeal angioma (cerebral malformations and tumors).

  4. Rubinstein–Taybi syndrome - Wikipedia

    en.wikipedia.org/wiki/Rubinstein–Taybi_syndrome

    During the summer of 1963, Dr. Taybi reported having evaluated seven children with such characteristics as broad thumbs and great toes, "unusual" facial features, and intellectual disabilities – these findings went on to appear in the American Journal of Diseases of Children documenting these characteristics as a syndrome. Dr.

  5. Pycnodysostosis - Wikipedia

    en.wikipedia.org/wiki/Pycnodysostosis

    The collar bones are often underdeveloped and malformed. The nails are flat, grooved, and dysplastic. High bone density, Acro-osteolysis and obtuse mandibular angle are the characteristic radiological findings of this disorder. [10] Pycnodysostosis also causes problems that may become evident with time.

  6. Diffuse idiopathic skeletal hyperostosis - Wikipedia

    en.wikipedia.org/wiki/Diffuse_idiopathic...

    In some, the x-ray findings may correspond to symptoms of back stiffness with flexion/extension or with mild back pain. [2] Back pain or stiffness may be worse in the morning. [ 4 ] Rarely, large anterior cervical spine osteophytes may affect the esophagus or the larynx and cause pain , difficulty swallowing [ 5 ] [ 6 ] or even dyspnea . [ 7 ]

  7. ATR-X syndrome - Wikipedia

    en.wikipedia.org/wiki/ATR-X_syndrome

    Alpha-thalassemia mental retardation syndrome (ATRX), also called alpha-thalassemia X-linked intellectual disability syndrome, nondeletion type or ATR-X syndrome, [1] is an X-linked recessive condition associated with a mutation in the ATRX gene. [2]

  8. Special needs - Wikipedia

    en.wikipedia.org/wiki/Special_needs

    In the United States "special needs" is a legal term applying in foster care, derived from the language in the Adoption and Safe Families Act of 1997. It is a diagnosis used to classify children as needing more services than those children without special needs who are in the foster care system.

  9. Floating–Harbor syndrome - Wikipedia

    en.wikipedia.org/wiki/Floating–Harbor_syndrome

    Floating–Harbor syndrome, also known as Pelletier–Leisti syndrome, is a rare disease with fewer than 50 cases described in the literature. [1] It is usually diagnosed in early childhood and is characterized by the triad of proportionate short stature with delayed bone age, characteristic facial appearance, and delayed speech development.