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A leiomyosarcoma (LMS) is a rare malignant (cancerous) smooth muscle tumor. [1] The word is from leio- 'smooth' myo- 'muscle' and sarcoma 'tumor of connective tissue'. The stomach, bladder, uterus, blood vessels, and intestines are examples of hollow organs made up of smooth muscles where LMS can be located; however, the uterus and abdomen are the most common sites.
Clear cell sarcoma is a sub-type of a rare form of cancer called a sarcoma. [1] It is known to occur mainly in the soft tissues and dermis . Rare forms were thought to occur in the gastrointestinal tract before they were discovered to be different and redesignated as gastrointestinal neuroectodermal tumors .
Desmoplastic melanoma, also known as neurotropic melanoma, or spindled melanoma [1] is a rare cutaneous condition characterized by a deeply infiltrating type of melanoma [2]: 696 with an abundance of fibrous matrix. It usually occurs in the head and neck region of older people with sun-damaged skin.
Spindle cell sarcoma is a type of connective tissue cancer. The tumors generally begin in layers of connective tissue , as found under the skin, between muscles, and surrounding organs, and will generally start as a small, inflamed lump, which grows in size.
In neurobiology, spindle cell refers to: Spindle neuron, also known as a von Economo neuron; In general medicine, a spindle cell may refer to the spindle-shaped cells that are found in certain types of tumor: Inflammatory fibroid polyp; Pigmented spindle cell nevus; Spindle cell carcinoma; Spindle cell lipoma; Spindle cell sarcoma
Histopathologic examination of the tumors in IMT generally reveals myofibroblastic spindle cell sheets in a myxoid background (i.e. a background matrix containing gelatinous mucopolysaccharides and non-sulfated glycosaminoglycans); the matrix also contains inflammatory cells, particularly plasma cells and lymphocytes occasionally mixed with ...
On histopathology, Spitz nevi characteristically have vertically arranged nests of nevus cells that have both a spindled and an epithelioid morphology. Apoptotic cells may be seen at the dermoepidermal junction. The main histologic differential diagnoses are pigmented spindle cell nevus and malignant melanoma.
A rhabdomyoblast is a cell type which is found in some rhabdomyosarcomas. [1] When found histologically, a rhabdomyoblast aids the diagnosis of embryonal, alveolar, spindle cell/sclerosing, and pleomorphic rhabdomyosarcomas; however, in a tumor, expression of the rhabdomyoblast phenotype is not the only factor in diagnosing a rhabdomyosarcoma.