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The causes of SIADH are commonly grouped into categories including: central nervous system diseases that directly stimulate the hypothalamus to release ADH, various cancers that synthesize and secrete ectopic ADH, various lung diseases, numerous drugs that may stimulate the release of ADH, enhance ADH effects, act as ADH analogues in the body ...
Nephrogenic diabetes insipidus is most common in its acquired forms, meaning that the defect was not present at birth. These acquired forms have numerous potential causes. The most obvious cause is a kidney or systemic disorder, including amyloidosis, [2] polycystic kidney disease, [3] electrolyte imbalance, [4] [5] or some other kidney defect. [2]
Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH) in turn can be caused by a number of problems. Some forms of cancer can cause SIADH, particularly small cell lung carcinoma but also a number of other tumors. A variety of diseases affecting the brain or the lung (infections, bleeding) can be the driver behind SIADH.
There are four types of DI, each with a different set of causes. [1] Central DI (CDI), also known as arginine vasopressin deficiency (AVP-D), [5] is due to a lack of vasopressin (antidiuretic hormone) production. [1] This can be due to injury to the hypothalamus or pituitary gland or due to genetics. [1]
The "vaptan" drugs act by directly blocking the action of vasopressin at its receptors (V 1A, V 1B and V 2).These receptors have a variety of functions, with the V 1A and V 2 receptors are expressed peripherally and involved in the modulation of blood pressure and kidney function respectively, while the V 1A and V 1B receptors are expressed in the central nervous system.
Singulair, a popular asthma medication, could be linked to severe side effects, including suicide, a study from the FDA found. Popular asthma drug Singulair could be linked to mental health side ...
1 Very common. 2 Common. 3 Uncommon. 4 Rare. 5 Unknown frequency. 6 Notes. 7 References. ... Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) [Note ...
The drugs that can cause hair loss include antihypertensive medications (such as ACE inhibitors or beta-blockers), cancer medications, statins, anticoagulants, antidepressants and medications that ...