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As little as 10 mL of pure methanol when drunk is metabolized into formic acid, which can cause permanent blindness by destruction of the optic nerve. 15 mL is potentially fatal, [1] although the median lethal dose is typically 100 mL (3.4 fl oz) (i.e. 1–2 mL/kg body weight of pure methanol). [4] Reference dose for methanol is 0.5 mg/kg/day. [9]
If as little as 10 ml of pure methanol is ingested, for example, it can break down into formic acid, which can cause permanent blindness by destruction of the optic nerve, and 30 ml is potentially fatal, [2] although the median lethal dose is typically 100 ml (3.4 fl oz) (i.e. 1–2 ml/kg body weight) of pure methanol. [3]
The eyes are also directly affected and this can cause blindness which is found in many people exposed to high levels of methanol." So far, five of the six who have died have been women .
The NHS warns that as little as 4ml of methanol can cause hallucinations and blindness. Half an hour to two hours after consuming methanol symptoms include drowsiness, confusion and irritability.
Methanol and its vapours are flammable. Moderately toxic for small animals – Highly toxic to large animals and humans (in high concentrations) – May be fatal/lethal or cause blindness and damage to the liver, kidneys, and heart if swallowed – Toxicity effects from repeated over exposure have an accumulative effect on the central nervous system, especially the optic nerve – Symptoms may ...
The recalled products contain methanol, or wood alcohol, which can be harmful if absorbed through the skin or fatal if ingested. ... and two people with permanent blindness and awaiting outcomes ...
Optic nerve damage in most inherited optic neuropathies is permanent and progressive. Leber's hereditary optic neuropathy (LHON) is the most frequently occurring mitochondrial disease, and this inherited form of acute or subacute vision loss predominantly affects young males.
Just small amounts of methanol can cause blindness, nausea and vomiting, while drinking as little as 30 milliliters (1 ounce) can be lethal.