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  2. Selective estrogen receptor modulator - Wikipedia

    en.wikipedia.org/wiki/Selective_estrogen...

    Selective estrogen receptor modulators (SERMs), also known as estrogen receptor agonists/antagonists (ERAAs), [1] [2] are a class of drugs that act on estrogen receptors (ERs). [3] Compared to pure ER agonists – antagonists (e.g., full agonists and silent antagonists ), SERMs are more tissue-specific, allowing them to selectively inhibit or ...

  3. Antihormone therapy - Wikipedia

    en.wikipedia.org/wiki/Antihormone_therapy

    Tamoxifen is also thought to lower the risk of breast cancer in those who have a predisposition or at risk. [9] Tamoxifen may be used in pre and postmenopausal women. [10] Toremifene is a similar SERM drug to tamoxifen, but is less common and only approved for treatment of metastatic cancer. Toremifene is generally prescribed once tamoxifen is ...

  4. Tamoxifen - Wikipedia

    en.wikipedia.org/wiki/Tamoxifen

    Tamoxifen is a selective estrogen receptor modulator (SERM). [48] Even though it is an antagonist in breast tissue it acts as partial agonist on the endometrium and has been linked to endometrial cancer in some women. Therefore, endometrial changes, including cancer, are among tamoxifen's side effects. [49]

  5. List of selective estrogen receptor modulators - Wikipedia

    en.wikipedia.org/wiki/List_of_selective_estrogen...

    Sivifene (A-007) was initially thought to be a SERM due to its structural similarity to tamoxifen but it was subsequently found not to bind to the estrogen receptor (ER). [8] Tesmilifene (DPPE; YMB-1002, BMS-217380-01) is also structurally related to tamoxifen but similarly does not bind to the ER and is not a SERM. [9] [10]

  6. Endoxifen - Wikipedia

    en.wikipedia.org/wiki/Endoxifen

    Endoxifen, also known as 4-hydroxy-N-desmethyltamoxifen, is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group as well as a protein kinase C (PKC) inhibitor. It is under development for the treatment of estrogen receptor-positive breast cancer and for the treatment of mania in bipolar disorder.

  7. Is Testosterone The Missing Piece Of The Menopause Puzzle? - AOL

    www.aol.com/testosterone-missing-piece-menopause...

    Here, Women's Health speaks to the women using the treatment, as well as the experts specializing in understanding the impact of such medications, to grapple with the promise – and the pitfalls ...

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