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Dosing should be based on regular measurements of thyroid-stimulating hormone (TSH) and T 4 levels in the blood. [5] Much of the effect of levothyroxine is following its conversion to triiodothyronine (T 3). [5] Levothyroxine was first made in 1927. [8] It is on the World Health Organization's List of Essential Medicines. [9]
Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...
It is used to treat hypothyroidism, [1] but less preferred than levothyroxine. [1] It is taken by mouth. [1] Maximal effects may take up to three weeks to occur. [1] Side effects may occur from excessive doses. [1] This may include weight loss, fever, headache, anxiety, trouble sleeping, arrhythmias, and heart failure. [1]
This may include weight loss, fever, headache, anxiety, trouble sleeping, arrhythmias, and heart failure. [1] Use in pregnancy and breastfeeding is generally safe. [2] [1] Regular blood tests are recommended to verify the appropriateness of the dose being taken. [1] Liothyronine was approved for medical use in 1956. [1]
Blood free thyroxine and TSH levels are monitored to help determine whether the dose is adequate. This is done 4–8 weeks after the start of treatment or a change in levothyroxine dose. Once the adequate replacement dose has been established, the tests can be repeated after 6 and then 12 months, unless there is a change in symptoms. [8]
Russia's military acknowledged that a bomb accidentally dropped by one of its warplanes caused a powerful blast in a Russian city not far from Ukraine's border, injuring two and scaring local ...
It determined that low-dose aspirin was not effective in reducing heart disease risk in Australian and American adults. Worth noting: White adults made up 96% of the study, so the findings may not ...
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
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