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The risk of venous thromboembolism with EE/CPA-containing birth control pills is similar to that with EE and gestodene-, desogestrel-, and drospirenone-containing birth control pills and about 50 to 80% higher than with EE and levonorgestrel-containing birth control pills.
The risk of thromboembolism varies with different types of birth control pills; compared with combined oral contraceptives containing levonorgestrel (LNG), and with the same dose of estrogen and duration of use, the rate ratio of deep venous thrombosis for combined oral contraceptives with norethisterone is 0.98, with norgestimate 1.19, with ...
Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender individuals ...
The progestogen-only pill, colloquially known as "minipill". For perfect use it is 99% effective and typical use is 91% effective. Side effects of the pill include headache, dizziness, nausea, sore breasts, spotting, mood changes, acne, bloating, etc. [clarification needed] One pill offers the benefit of only having to be taken once a week:
These differences make EE more favorable for use in birth control pills than estradiol, though also result in an increased risk of blood clots and certain other rare adverse effects. [7] EE was developed in the 1930s and was introduced for medical use in 1943. [13] [14] The medication started being used in birth control pills in the 1960s. [15]
Side effects can include nausea, headache, blood clots, breast pain, depression, and liver problems. [3] Use is not recommended during pregnancy, the initial three weeks after childbirth, and in those at high risk of blood clots. [3] However, it may be started immediately after a miscarriage or abortion. [5]
Norgestrel was first introduced, as a birth control pill in combination with ethinylestradiol, under the brand name Eugynon in Germany in 1966. [ 9 ] [ 10 ] It was subsequently marketed as a combined birth control pill with ethinylestradiol in the United States under the brand name Ovral in 1968, and was marketed in many other countries as well.
Etonogestrel is effective as a means of birth control and lasts at least three or four years with some data showing effectiveness for five years. [9] [11] Following removal, fertility quickly returns. [15] Side effects of etonogestrel include menstrual irregularities, breast tenderness, mood changes, acne, headaches, vaginitis, and others. [4]
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