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Congenital varicella syndrome is a rare disease resulting from Varicella Zoster virus (VZV) infection during the period of gestation. Viremia during the primary infection can result in transplacental transmission of the infection to the developing fetus .
Varicella is a particular problem in hospitals when there are patients with immune systems weakened by drugs (e.g., high-dose steroids) or HIV. [ 75 ] Secondary bacterial infection of skin lesions, manifesting as impetigo , cellulitis , and erysipelas , is the most common complication in healthy children.
This medication is usually well tolerated though mild side effects such as pain or blistering are common. [25] There is no high-quality evidence for cimetidine. [26] However, oral cimetidine has been used as an alternative treatment for the pediatric population as it is generally well tolerated and less invasive. [27]
Varicella zoster virus (VZV), also known as human herpesvirus 3 (HHV-3, HHV3) or Human alphaherpesvirus 3 (taxonomically), is one of nine known herpes viruses that can infect humans. It causes chickenpox (varicella) commonly affecting children and young adults, and shingles (herpes zoster) in adults but rarely in children.
Immunoglobulin therapy is the use of a mixture of antibodies (normal human immunoglobulin) to treat several health conditions. [13] [14] These conditions include primary immunodeficiency, immune thrombocytopenic purpura, chronic inflammatory demyelinating polyneuropathy, Kawasaki disease, certain cases of HIV/AIDS and measles, Guillain–Barré syndrome, and certain other infections when a ...
The MMRV protects against measles, mumps, rubella and varicella. [48] Some side effects of the MMR vaccine are [2] fever (1 in 6) mild rash (1 in 20) swelling of the glands in cheeks or neck (1 in 75) If these occur, it is usually within 7–12 days after the shot. They occur less often after the second dose Some more moderate side effects are
Since the discovery in the mid-1970s, it has been used as an effective drug for the treatment of infections caused by most known species of the herpesvirus family, including herpes simplex and varicella zoster viruses. Nucleosides isolated from a Caribbean sponge, Cryptotethya crypta, were the basis for the synthesis of aciclovir.
In such cases, the effects may be seen first at birth. [citation needed] Symptoms of a vertically transmitted infection may include fever and flu-like symptoms. The newborn is often small for gestational age. A petechial rash on the skin may be present, with small reddish or purplish spots due to bleeding from capillaries under the skin.