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  2. The best muscle pain relief creams of 2025, according to ...

    www.aol.com/lifestyle/best-muscle-pain-relief...

    Cost: $7 | Active ingredients: Lidocaine | Type: Cream | Amount: 4.3 ounces. Lidocaine is another popular ingredient found in pain relief creams. It's a topical anesthetic that's often used to ...

  3. Capsaicin - Wikipedia

    en.wikipedia.org/wiki/Capsaicin

    One 2017 review of clinical studies having limited quality found that high-dose topical capsaicin (8%) compared with control (0.4% capsaicin) provided moderate to substantial pain relief from post-herpetic neuralgia, HIV-neuropathy, and diabetic neuropathy. [21] Although capsaicin creams have been used to treat psoriasis for reduction of ...

  4. Best arthritis pain relief cream of 2024, according to experts

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    Penetrex's Warming Pain Relief Cream is a vegan formula that aids in soothing muscle and joint pain with the use of capsaicin, arnica and MSM. Capsaicin has been shown to reduce pain signals ...

  5. Diabetic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Diabetic_neuropathy

    Diabetes is the leading known cause of neuropathy in developed countries, and neuropathy is the most common complication and greatest source of morbidity and mortality in diabetes. A systematic review has found that diabetic peripheral neuropathy affects 30% of diabetes patients. [ 1 ]

  6. Zucapsaicin - Wikipedia

    en.wikipedia.org/wiki/Zucapsaicin

    It begins a few hours after capsaicin application and may last even several weeks. [16] The reversible desensitization was found useful in the treatment of pain, whereas the site-specific ablation of sensory nerves transmitting pain stimuli is a promising approach (‘molecular scalpel’) to achieve a permanent pain relief in patients ...

  7. Here's the #1 Cream for Arthritis, According to Experts - AOL

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  8. TRPV1 - Wikipedia

    en.wikipedia.org/wiki/TRPV1

    TRPV1 activation caused by its agonist capsaicin was shown to induce G0-G1 cell arrest and apoptosis in leukemic cell lines, adult T-cell leukaemia and multiple myeloma. Capsaicin reduces the expression of anti-apoptotic protein Bcl-2 and it also promotes activation of p53, a tumour-suppressor protein known as a major regulator of cell death.

  9. Proximal diabetic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Proximal_diabetic_neuropathy

    Proximal diabetic neuropathy, also known as diabetic amyotrophy, is a complication of diabetes mellitus that affects the nerves that supply the thighs, hips, buttocks and/or lower legs. Proximal diabetic neuropathy is a type of diabetic neuropathy characterized by muscle wasting, weakness, pain, or changes in sensation/numbness of the leg.

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