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A lipoma is a benign tumor made of fat tissue. [1] They are generally soft to the touch, movable, and painless. [1] They usually occur just under the skin, but occasionally may be deeper. [1]
The only effective treatments for lipomas caused by familial multiple lipomatosis are liposuction or surgical removal. [6] Steroid injections may also be used to shrink the tumors by causing local fat atrophy. [7] Patients with the condition often seek removal when the lipomas are large, disfiguring, or cause pain. [2]
Other entities which are accompanied by multiple lipomas include Proteus syndrome, Cowden syndrome and related disorders due to PTEN gene mutations, benign symmetric lipomatosis (Madelung disease), Dercum's Disease, familial lipodystrophy, hibernomas, epidural steroid injections with epidural lipomatosis, [6] and familial angiolipomatosis.
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Lipomas are usually diagnosed clinically, although imaging (ultrasound, computed tomography, or magnetic resonance imaging) may be utilized to assist with the diagnosis of lipomas in atypical locations. [24] The main treatment for lipomas is surgical excision, after which the tumor is examined with histopathology to confirm the diagnosis. [24]
Dercum's disease is a rare condition characterized by multiple painful fatty tumors, called lipomas, that can grow anywhere in subcutaneous fat across the body. [1] Sometimes referred as adiposis dolorosa in medical literature, Dercum’s disease is more of a syndrome than a disease (because it has several clinically recognizable features, signs, and symptoms that are characteristic of it and ...
Lipedema is classified by stage: Stage 1: Normal skin surface with enlarged hypodermis (lipedema fat). Stage 2: Uneven skin with indentations in fat and larger hypodermal masses (lipomas). Stage 3: Bulky extrusions of skin and fat cause large deformations especially on the thighs and around the knees.
Benign symmetric lipomatosis, also known as Madelung's disease, is an adult-onset skin condition characterized by extensive symmetric fat deposits in the head, neck, and shoulder girdle area. [1]
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