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Progeroid syndromes (PS) are a group of rare genetic disorders that mimic physiological aging, making affected individuals appear to be older than they are. [1] [2] The term progeroid syndrome does not necessarily imply progeria (Hutchinson–Gilford progeria syndrome), which is a specific type of progeroid syndrome.
When this gene mutates, an abnormal form of lamin A protein called progerin is produced. Progeroid syndromes are a group of diseases that cause individuals to age faster than usual, leading to them appearing older than they actually are. People born with progeria typically live until their mid- to late-teens or early twenties.
The term childhood disease refers to disease that is contracted or becomes symptomatic before the age of 18 or 21 years old. Many of these diseases can also be contracted by adults. Some childhood diseases include:
Roughly 20% of persons greater than 60 years of age have a neurological disorder, with episodic disorders being the most common, followed by extrapyramidal movement disorders and nerve disorders. [14] Diseases commonly associated with old age include Multiple system atrophy [15] Parkinson's disease [16] Alzheimer's disease [17] Stroke. [18]
One proposed mechanism for the observed age-related plasticity deficits in animals is the result of age-induced alterations in calcium regulation. [11] The changes in the organism's abilities to handle calcium will ultimately influence neuronal firing and the ability to propagate action potentials , which in turn would affect the ability of the ...
An aging-associated disease (commonly termed age-related disease, ARD) is a disease that is most often seen with increasing frequency with increasing senescence. They are essentially complications of senescence, distinguished from the aging process itself because all adult animals age ( with rare exceptions ) but not all adult animals ...
Additionally, systematic desensitization can be used to decrease children's fear associated with some medical treatments, such as imaging or invasive procedures. [19] One of the more studied interventions for the psychological management of chronic physical illness in children is Cognitive Behavioral Therapy (CBT). CBT is used to build ...
[1] [2] These changes play an important role in physiological development and are important in providing appropriate diagnosis and treatment of bleeding and clotting disorders (e.g. thrombosis). [ 3 ] [ 4 ] The age-specific differences in the blood clotting system may contribute to the fact that children are less prone to developing thrombosis ...
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