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Spironolactone. Spironolactone is a once-a-day tablet that can stop hair loss from progressing and encourage new hair growth. ... Laser therapy may help FPHL, alopecia areata, and hair loss after ...
A prescription medication, spironolactone blocks androgen production that decreases the amount of DHT, the hormone that causes hair follicles to shrink and hair shafts to become thinner and finer.
The onset of action of the antimineralocorticoid effects of spironolactone is relatively slow, with the peak effect sometimes occurring 48 hours or more after the first dose. [1] [24] Canrenone is an antagonist of the MR as is spironolactone, [25] but it is slightly more potent in comparison.
It may be effective in helping promote hair growth in both men and women with androgenic alopecia. [20] [21] About 40% of men experience hair regrowth after 3–6 months. [22] It is the only topical product that is FDA approved in America for androgenic hair loss. [20] However, increased hair loss has been reported. [23] [24]
Spironolactone can be used in the treatment of female-pattern hair loss (pattern scalp hair loss in women). [69] There is tentative low quality evidence supporting its use for this indication. [ 70 ] Although apparently effective, not all cases of female-pattern hair loss are dependent on androgens.
While the FDA hasn’t approved oral minoxidil for hair loss, clinical trials have shown it’s quite effective for hair growth at various doses (0.25 to 2.5 mg daily). Spironolactone .
Dutasteride is sometimes used as a component of hormone therapy for transgender women in combination with an estrogen and/or another antiandrogen such as spironolactone. [7] It may be useful for preventing and treating scalp hair loss and can also be used as a general antiandrogen for in those who have issues tolerating spironolactone, though as a α-reductase inhibitor it has limited effects ...
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