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At the end of 2023, kidney cancer specialists got yet another arrow to add to their quivers: The FDA approved the drug belzutifan, a medication that effectively suffocates tumors by blocking a ...
November 23, 2022 at 11:00 AM. Researchers say a new study of kidney cancer offers hope for treating the disease using existing drugs. The study of the cancer at a single-cell level has discovered ...
175,000 [ 5 ] Kidney cancer, also known as renal cancer, is a group of cancers that starts in the kidney. [ 4 ] Symptoms may include blood in the urine, a lump in the abdomen, or back pain. [ 1 ][ 2 ][ 3 ] Fever, weight loss, and tiredness may also occur. [ 1 ][ 2 ][ 3 ] Complications can include spread to the lungs or brain.
Sorafenib, sold under the brand name Nexavar, [3] is a kinase inhibitor drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), FLT3-ITD positive AML and radioactive iodine resistant advanced thyroid carcinoma.
Bevacizumab, sold under the brand name Avastin among others, is a monoclonal antibody medication used to treat a number of types of cancers and a specific eye disease. [30] [28] For cancer, it is given by slow injection into a vein (intravenous) and used for colon cancer, lung cancer, ovarian cancer, glioblastoma, hepatocellular carcinoma, and renal-cell carcinoma. [31]
It was approved in 2014. Nivolumab is approved to treat melanoma, lung cancer, kidney cancer, bladder cancer, head and neck cancer, and Hodgkin's lymphoma. [159] A 2016 clinical trial for non-small cell lung cancer failed to meet its primary endpoint for treatment in the first-line setting, but is FDA-approved in subsequent lines of therapy. [160]
Though the odds of getting kidney cancer are rare (about a 1% chance for women and a 2% chance for men), the number of new diagnoses has been on the rise in recent years. Part of this could be due ...
AOH1996 is an experimental anticancer medication which acts as a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) and is in Phase I clinical trials at City of Hope as of August 2023 for the treatment of solid tumors. [1][2][3][4] AOH1996 was created to target a post-translationally modified isoform of PCNA, termed caPCNA ...
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