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The Henderson–Hasselbalch equation can be used to model these equilibria. It is important to maintain this pH of 7.4 to ensure enzymes are able to work optimally. [10] Life threatening Acidosis (a low blood pH resulting in nausea, headaches, and even coma, and convulsions) is due to a lack of functioning of enzymes at a low pH. [10]
Therefore, pH values on the different scales cannot be compared directly because of differences in the solvated proton ions, such as lyonium ions, which require an insolvent scale that involves the transfer activity coefficient of hydronium/lyonium ion. pH is an example of an acidity function, but others can be defined.
A buffer solution is a solution where the pH does not change significantly on dilution or if an acid or base is added at constant temperature. [1] Its pH changes very little when a small amount of strong acid or base is added to it. Buffer solutions are used as a means of keeping pH at a nearly constant value in a wide variety of chemical ...
The isoelectric point (pI, pH(I), IEP), is the pH at which a molecule carries no net electrical charge or is electrically neutral in the statistical mean. The standard nomenclature to represent the isoelectric point is pH(I). [1] However, pI is also used. [2] For brevity, this article uses pI.
Metabolic acidosis can lead to acidemia, which is defined as arterial blood pH that is lower than 7.35. [6] Acidemia and acidosis are not mutually exclusive – pH and hydrogen ion concentrations also depend on the coexistence of other acid-base disorders; therefore, pH levels in people with metabolic acidosis can range from low to high.
The pH of urine normally vary between 4.5 and 8 with the first urine produced in the morning generally being more acidic and the urine produced after meals generally more alkaline. [4] Normal reference values are not provided for urine pH as the variation is too wide and results have to be considered in the context of the other quantifiable ...
Jeffrey Stephen Wigand (/ ˈ w aɪ ɡ æ n d /; born December 17, 1942) is an American biochemist and whistleblower.. He is a former vice president of research and development at Brown & Williamson in Louisville, Kentucky, who worked on the development of reduced-harm cigarettes and in 1996 blew the whistle on tobacco tampering at the company.
Multiple choice items consist of a stem and several alternative answers. The stem is the opening—a problem to be solved, a question asked, or an incomplete statement to be completed. The options are the possible answers that the examinee can choose from, with the correct answer called the key and the incorrect answers called distractors. [4]