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  2. Canine discoid lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Canine_discoid_lupus...

    Discoid lupus erythematosus (DLE) is an uncommon autoimmune disease of the basal cell layer of the skin. It occurs in humans [1] and cats, more frequently occurring in dogs. It was first described in dogs by Griffin and colleagues in 1979. [2][3] DLE is one form of cutaneous lupus erythematosus (CLE). DLE occurs in dogs in two forms: a ...

  3. Lupus - Wikipedia

    en.wikipedia.org/wiki/Lupus

    Lupus. Lupus, technically known as systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [1] Common symptoms include painful and swollen joints, fever, chest pain, hair loss, mouth ...

  4. Lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Lupus_erythematosus

    Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs. The most common and most severe form is systemic lupus erythematosus.

  5. Discoid lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Discoid_lupus_erythematosus

    Dermatology, Immunology. Discoid lupus erythematosus is the most common type of chronic cutaneous lupus (CCLE), an autoimmune skin condition on the lupus erythematosus spectrum of illnesses. [1][2] It presents with red, painful, inflamed and coin-shaped patches of skin with a scaly and crusty appearance, most often on the scalp, cheeks, and ears.

  6. Rheumatoid arthritis - Wikipedia

    en.wikipedia.org/wiki/Rheumatoid_arthritis

    30,000 (2015) [ 4 ] Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. [ 1 ] It typically results in warm, swollen, and painful joints. [ 1 ] Pain and stiffness often worsen following rest. [ 1 ] Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the ...

  7. Autoimmune disease - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_disease

    An autoimmune disease is a condition that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms. [1] It is estimated that there are more than 80 recognized autoimmune diseases, with recent scientific evidence suggesting ...

  8. Anti-SSA/Ro autoantibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-SSA/Ro_autoantibodies

    The presence of Anti-SSA/Ro in pregnant women with SLE is associated with an increased risk of neonatal lupus erythematosus which can be accompanied by congenital heart block (CHB) in the fetus. [12] SLE-related symptoms in infants that arise from Anti-Ro/SSA resolve in about six months as the mother's antibodies leave the baby's system. [3]

  9. Epigenetics of autoimmune disorders - Wikipedia

    en.wikipedia.org/wiki/Epigenetics_of_autoimmune...

    Systemic lupus erythematosus (SLE) Systemic lupus erythematosus is the most common form of lupus and is a condition in which the immune system attacks healthy bodily tissue causing wide-spread inflammation and tissue damage across many organ systems. Hypomethylation is observed across the epigenome in those with systemic lupus.

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