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Their body is populated by adult stem cells called neoblasts, which planarians use for regenerating missing body parts. [6] Many species are able to regenerate any missing organ, which has made planarians a popular model in research of regeneration and stem cell biology. [7]
Synonyms. Dugesia mediterranea. Benazzi, Baguñà, Ballester, Puccinelli & Del Papa, 1975. Schmidtea mediterranea is a freshwater triclad that lives in southern Europe and Tunisia. [2] It is a model for regeneration, stem cells and development of tissues such as the brain and germline. [3][4]
Neoblasts (ˈniːəʊˌblæst) are adult stem cells found in planarian flatworms. They are the only dividing planarian cells, and they produce all cell types, including the germline. [1][2] Neoblasts are abundant in the planarian parenchyma, and comprise up to 30 percent of all cells. [1] Following injury, neoblasts rapidly divide and generate ...
Regeneration in biology is the process of renewal, restoration, and tissue growth that makes genomes, cells, organisms, and ecosystems resilient to natural fluctuations or events that cause disturbance or damage. [ 1 ] Every species is capable of regeneration, from bacteria to humans. [ 2 ][ 3 ][ 4 ] Regeneration can either be complete [ 5 ...
Alejandro Sánchez Alvarado is a molecular biologist, an Emeritus Investigator of the Howard Hughes Medical Institute, and President and Chief Scientific Officer of the Stowers Institute for Medical Research. The Sánchez Alvarado Laboratory focuses on understanding the regenerative capabilities of the planarian flatworm Schmidtea mediterranea.
The natural movement promoted the alignment of the new fibers and tendocytes with the natural alignment found in uninjured tendons. Stem cell treatment not only allowed more horses to return to full duty and also greatly reduced the re-injury rate over a three-year period. [23] The use of embryonic stem cells has also been applied to tendon repair.
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