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Hydralazine is a direct vasodilator used orally to treat essential hypertension, among other diseases, and intravenously to rapidly reduce blood pressure in hypertensive urgency or emergency. Per JNC 8 guidelines, it is not a first-line agent for the treatment of essential hypertension.
Hydralazine is a direct-acting smooth muscle relaxant and acts as a vasodilator primarily in resistance arterioles, also known as the smooth muscle of the arterial bed. The molecular mechanism involves inhibition of inositol trisphosphate-induced Ca 2+ release from the sarcoplasmic reticulum in arterial smooth muscle cells.
Hydralazine is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). This lowers blood pressure and allows blood to flow more easily through your veins and arteries.
Hydralazine is a vasodilator - this means it relaxes smooth muscle inside blood vessels, making the blood vessels wider, and allowing more blood to flow through. This reduces how much force the heart has to exert to pump blood through the blood vessels, and reduces blood pressure.
Hydralazine works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. This medicine is available only with your doctor's prescription.
Hydralazine lowers blood pressure by relaxing your blood vessels. Relaxed blood vessels cause the heart to work harder, which can lead to a heart attack. Mitral Valvular Rheumatic Heart...
Hydralazine is used to treat high blood pressure. Hydralazine is in a class of medications called vasodilators. It works by relaxing the blood vessels so that blood can flow more easily through the body.