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Clonidine has some role in the treatment of spasticity, acting principally by inhibiting excessive sensory transmission below the level of injury [clarify]. Its use, however, is mainly as a second or third line agent, due to side effects such as hypotension, bradycardia, and drowsiness. [42]
It was also found that children at this age are more sensitive to side effects and should be closely monitored. [184] Evidence suggests that careful assessment and highly individualized behavioural interventions significantly improve both social and academic skills, [187] while medication only treats the symptoms of the disorder. "One of the ...
At least three children ended up in the hospital after taking a liquid form of clonidine dispensed at a Kentucky pharmacy 5-Year-Old in ICU from Potentially Bad Batch of ADHD Medicine, 2 Other ...
Clonidine is becoming increasingly popular as a premedication for children. One drawback of clonidine is that it can take up to 45 minutes to take full effect. [3] In children, clonidine has been found to be equal to and possibly superior to benzodiazepines as a premedication. It has a more favourable side effect profile.
An 8-year-old boy died after a Colorado pharmacy gave him a dosage of medication 1,000 times higher than what he was prescribed, his mother said.
Common side effects include sleepiness, constipation, and dry mouth. [9] Other side effects may include low blood pressure and urinary problems. [11] The FDA has categorized Guanfacine as "Category B" in pregnancy, which means animal-reproduction studies have not demonstrated a fetal risk or an adverse effect during pregnancy or breastfeeding.
Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.
Naloxone is an opioid antagonist: a medication used to reverse or reduce the effects of opioids. [13] For example, it is used to restore breathing after an opioid overdose. It is also known as Narcan. [13] Effects begin within two minutes when given intravenously, five minutes when injected into a muscle, [13] and ten minutes as a nasal spray. [14]
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