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Bioinformatics is the name given to these mathematical and computing approaches used to glean understanding of biological processes. Common activities in bioinformatics include mapping and analyzing DNA and protein sequences, aligning DNA and protein sequences to compare them, and creating and viewing 3-D models of protein structures.
Bioinformatics: Research, development, or application of computational tools and approaches for expanding the use of biological, medical, behavioral or health data, including those to acquire, store, organize, archive, analyze, or visualize such data. [1]
The concept of biological computation proposes that living organisms perform computations, and that as such, abstract ideas of information and computation may be key to understanding biology.
Whereas traditional bioinformatics is a wide subject it has a large focus on molecular biology, pharmaceutical bioinformatics more specifically targets chemical-biological interaction and exploratory focus of chemical and biological interactors using e.g. cheminformatics and chemometrics methods.
Biological computers use biologically derived molecules — such as DNA and/or proteins — to perform digital or real computations.. The development of biocomputers has been made possible by the expanding new science of nanobiotechnology.
Machine learning in bioinformatics is the application of machine learning algorithms to bioinformatics, [1] including genomics, proteomics, microarrays, systems biology, evolution, and text mining. [ 2 ] [ 3 ]
The NCBI houses a series of databases relevant to biotechnology and biomedicine and is an important resource for bioinformatics tools and services. Major databases include GenBank for DNA sequences and PubMed, a bibliographic database for biomedical literature.
Pevzner is interested in new approaches to teaching computational molecular biology at both undergraduate and graduate level, [7] [8] serving as a founding instructor for the bioinformatics specialization on Coursera [9] and having written several books on bioinformatics and computational biology. [4] [10] [11] [1]