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Multidrug and toxin extrusion protein 1 (MATE1), also known as solute carrier family 47 member 1, is a protein that in humans is encoded by the SLC47A1 gene. [ 5 ] [ 6 ] SLC47A1 belongs to the MATE (multidrug and toxic compound extrusion) family of transporters that are found in bacteria, archaea and eukaryotes.
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These proteins are predicted to have 12 alpha-helical transmembrane regions, some of the animal proteins may have an additional C-terminal helix. [4] The X-ray structure of the NorM was determined to 3.65 Å, revealing an outward-facing conformation with two portals open to the outer leaflet of the membrane and a unique topology of the predicted 12 transmembrane helices distinct from any other ...
These were all considered part of full Internet service. Also several free web hosting services such as Geocities provided free web space for personal web pages. [2] These free web hosting services would typically include web-based site management and a few pre-configured scripts to easily integrate an input form or guestbook script into the ...
n/a Ensembl ENSG00000180638 n/a UniProt Q86VL8 n/a RefSeq (mRNA) NM_001099646 NM_001256663 NM_152908 n/a RefSeq (protein) NP_001093116 NP_001243592 NP_690872 n/a Location (UCSC) Chr 17: 19.68 – 19.72 Mb n/a PubMed search n/a Wikidata View/Edit Human Multidrug and toxin extrusion protein 2 is a protein which in humans is encoded by the SLC47A2 gene. Function This gene encodes a protein ...
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[1] [2] Nevertheless, guggulsterone is an ingredient in many nutritional supplements. Guggulsterone was also found to have interactions with the viral ADP ribose phosphatase enzyme of SARS-CoV-2 and has been proposed as a potential candidate for the development of therapeutics for the treatment of COVID-19.