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Acute liver failure; Acute liver failure (with hepatocellular necrosis and sinusoidal bleeding) from Marburg virus, a rare cause: Specialty: Gastroenterology, hepatology, intensive care medicine Symptoms: Jaundice, excessive bleeding, altered state of consciousness, hyperdynamic circulation, hepatocellular necrosis, low blood pressure ...
Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, chronic liver failure or chronic hepatic failure and end-stage liver disease, is an acute condition of the liver in which the normal functioning tissue, or parenchyma, is replaced with scar tissue and regenerative nodules as a result of chronic liver disease.
Despite treatment, re-bleeding occurs in about 7–16% of those with upper GI bleeding. [3] In those with esophageal varices, bleeding occurs in about 5–15% a year and if they have bled once, there is a higher risk of further bleeding within six weeks. [13] Testing and treating H. pylori if found can prevent re-bleeding in those with peptic ...
Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. Two forms are recognised, acute and chronic (cirrhosis). [ 1 ] Recently, a third form of liver failure known as acute-on-chronic liver failure ( ACLF ) is increasingly being recognized.
With early treatment liver failure is rare. [6] Death occurs in about 0.1% of cases. [1] Paracetamol poisoning was first described in the 1960s. [6] Rates of poisoning vary significantly between regions of the world. [8] In the United States more than 100,000 cases occur a year. [1]
Hepatic veno-occlusive disease (VOD) or veno-occlusive disease with immunodeficiency is a potentially life-threatening condition in which some of the small veins in the liver are obstructed. It is a complication of high-dose chemotherapy given before a bone marrow transplant or excessive exposure to hepatotoxic pyrrolizidine alkaloids .
The Liver Injury Scale classification (2018 revision) [1] [2] [10] Grade Subcapsular hematoma Laceration Vascular injury I <10% surface area <1 cm in depth - II: 10–50% surface area: 1–3 cm - III >50% or >10 cm >3 cm Any injury in the presence of a liver vascular injury or active bleeding contained within liver parenchyma IV: 25–75% of a ...
Treatment of hepatomegaly varies with the cause, so accurate diagnosis is the first concern. In auto-immune liver disease, prednisone and azathioprine may be used for treatment. [3] In lymphoma the treatment options include single-agent (or multi-agent) chemotherapy and regional