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[6] [6] Peak concentrations of phentermine are reached 6 hours following oral administration of a dose of 15 mg. [6] The steady-state levels of phentermine with continuous administration have been found to be around 200 ng/mL in clinical studies. [6] The oral bioavailability of phentermine is not affected by intake of a high-fat meal. [6]
Phentermine and topiramate was developed by Vivus, a California pharmaceutical company. In December 2009, Vivus, Inc. submitted a new drug application (NDA) to the FDA and on 1 March 2010, Vivus, Inc. announced that the FDA accepted the NDA for review.
In 1984, researchers at the University of Rochester Medical Center reported that they had performed a double-blind, controlled clinical trial comparing phentermine alone, fenfluramine alone, a combination of phentermine and fenfluramine, and placebo, for weight loss in humans. Weight loss in those receiving the fen-phen combination was ...
Two Kentucky pharmacists who allegedly fraudulently billed insurance programs more than $1 million have been charged in an investigation of health care fraud.
The doctor and a nurse who worked for her were convicted in federal court a charges related to prescribing pain pills. Kentucky doctor sentenced for improper prescribing, ‘exceptionally high ...
Merced attended medical school in the Philippines, graduating in 1970, and has been licensed in Kentucky since 1986. His specialty is family medicine. Show comments
Western Kentucky Rural Healthcare Network TriStar Greenview Regional Hospital: Warren: Bowling Green: 211: General: HCA Healthcare Twin Lakes Regional Medical Center: Grayson: Leitchfield: 75: General: 1951: University of Kentucky Children's Hospital: Fayette: Lexington: Level I pediatric trauma center: UK HealthCare University of Louisville ...
Chemically, it is a substituted phenethylamine and amphetamine and is closely related to phentermine and methamphetamine. [ 4 ] [ 9 ] [ 1 ] Mephentermine was first described and introduced for medical use by 1952. [ 10 ]