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In animal tooth development, cementogenesis is the formation of cementum, one of the three mineralized substances of a tooth.Cementum covers the roots of teeth and serves to anchor gingival and periodontal fibers of the periodontal ligament by the fibers to the alveolar bone (some types of cementum may also form on the surface of the enamel of the crown at the cementoenamel junction (CEJ)).
There exists a normal variation in the relationship of the cementum and the enamel at the cementoenamel junction. In about 60–65% of teeth, the cementum overlaps the enamel at the CEJ, while in about 30% of teeth, the cementum and enamel abut each other with no overlap.
The dentinocemental junction (DCJ) is formed because of the apposition of cementum over the dentin. [ 6 ] [ 7 ] This interface is not as defined, either clinically or histologically, as that of the dentinoenamel junction (DEJ), given that cementum and dentin are of common embryological background, unlike that of enamel and dentin.
Tooth development begins at week 6 in utero, in the oral epithelium. The process is divided into three stages: Initiation; Morphogenesis and; Histogenesis [2]; At the end of week 7 i.u., localised proliferations of cells in the dental laminae form round and oval swellings known as tooth buds, which will eventually develop into mesenchymal cells and surround the enamel organ.
The hyaline layer aids cementum in binding to the dentin. [ 2 ] The rationale behind the use of enamel matrix derivative proteins, such as Emdogain, in trying to stimulate reproduction of cementum in periodontal bony defects is based on the presence of enamel matrix-like proteins within the hyaline layer.
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The dental follicle → will develop to become the periodontal ligament, the cementum and the alveolar bone; The dental papilla → will develop to become the dental pulp and the dentine; The enamel organ → will develop to create the enamel solely; Till this point, no dental tissues have been created yet.