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Calcium channel blocker poisoning, calcium channel blocker overdose: A 20% lipid emulsion commonly used for calcium channel blocker toxicity: Specialty: Emergency medicine: Symptoms: Slow heart rate, low blood pressure, nausea, vomiting, sleepiness [1] [2] Complications: Cardiac arrest [2] Usual onset: Within 6 hours [2] Causes
Symptoms that affect the sensory and motor systems seem to develop symmetrically. For example, if the right foot is affected, the left foot is affected simultaneously or soon becomes affected. [1] In most cases, the legs are affected first, followed by the arms. The hands usually become involved when the symptoms reach above the ankle. [3]
Firstly, the doctor will ask the patient about their alcohol consumption habits, as well as any symptoms they may have experienced, such as shortness of breath or swelling in the legs. [8] They may also perform a physical examination to check for signs of heart failure, such as an enlarged heart or fluid buildup in the lungs.
Amlodipine works partly by vasodilation (relaxing the arteries and increasing their diameter). [10] It is a long-acting calcium channel blocker of the dihydropyridine type. [10] Amlodipine was patented in 1982, and approved for medical use in 1990. [12] It is on the World Health Organization's List of Essential Medicines. [13]
The DSM-5 defines alcohol intoxication as at least one of the following symptoms that developed during or close after alcohol ingestion: slurred speech, incoordination, unsteady walking/movement, nystagmus (uncontrolled eye movement), attention or memory impairment, or near unconsciousness or coma. [16]
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Symptoms of varying BAC levels. Additional symptoms may occur. The short-term effects of alcohol consumption range from a decrease in anxiety and motor skills and euphoria at lower doses to intoxication (drunkenness), to stupor, unconsciousness, anterograde amnesia (memory "blackouts"), and central nervous system depression at higher doses.
Alcohol hallucinosis is a rather uncommon alcohol-induced psychotic disorder almost exclusively seen in chronic alcoholics who have many consecutive years of severe and heavy drinking during their lifetime. [3] Alcoholic hallucinosis develops about 12 to 24 hours after the heavy drinking stops suddenly, and can last for days.