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  2. Regadenoson - Wikipedia

    en.wikipedia.org/wiki/Regadenoson

    Regadenoson, sold under the brand name Lexiscan among others, is an A 2A adenosine receptor agonist that is a coronary vasodilator that is commonly used in pharmacologic stress testing. It produces hyperemia quickly and maintains it for a duration that is useful for radionuclide myocardial perfusion imaging . [ 1 ]

  3. Mitotic inhibitor - Wikipedia

    en.wikipedia.org/wiki/Mitotic_inhibitor

    (Kaposi sarcoma is a cancer of the skin and mucous membranes that is commonly found in patients with acquired immunodeficiency syndrome, AIDS). It is so effective that some oncologists refer to the period before 1994 as the "pre-taxol" era for treating breast cancer. [30]

  4. Bcr-Abl tyrosine-kinase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Bcr-Abl_tyrosine-kinase...

    Only cytotoxic drugs such as busulfan, hydroxyurea or interferon-alpha (rIFN-α) were utilized. Even though the first Bcr-Abl TK inhibitor was named "the magic bullet" to cure cancer by Time magazine, a second generation of Bcr-Abl TKI was subsequently developed to combat the initial resistance that emerged. [2]

  5. ALK inhibitor - Wikipedia

    en.wikipedia.org/wiki/ALK_inhibitor

    ALK inhibitors are anti-cancer drugs that act on tumours with variations of anaplastic lymphoma kinase (ALK) such as an EML4-ALK translocation. [1] They fall under the category of tyrosine kinase inhibitors , which work by inhibiting proteins involved in the abnormal growth of tumour cells.

  6. US FDA puts partial clinical hold on BioNTech's early-stage ...

    www.aol.com/news/us-fda-puts-partial-clinical...

    The drug, an antibody-drug conjugate (ADC), was being studied in a trial sponsored by China-based MediLink, in patients with types of non-small cell lung cancer or breast cancer who have received ...

  7. Immunosuppressive drug - Wikipedia

    en.wikipedia.org/wiki/Immunosuppressive_drug

    Non-melanoma skin cancer (NMSC) after kidney transplantation is common and can result in significant morbidity and mortality. The results of several studies suggest that calcineurin inhibitors have oncogenic properties mainly linked to the production of cytokines that promote tumor growth, metastasis and angiogenesis.

  8. US FDA puts clinical hold on Iovance's cancer therapy trial

    www.aol.com/news/us-fda-places-clinical-hold...

    (Reuters) -The U.S. health regulator has placed a clinical hold on Iovance Biotherapeutics' trial of its experimental cell therapy in lung cancer patients after a patient death, the company said ...

  9. Premedication - Wikipedia

    en.wikipedia.org/wiki/Premedication

    Premedication before chemotherapy for cancer often consists of drug regimens (usually 2 or more drugs, e.g. dexamethasone, diphenhydramine and omeprazole) given to a patient minutes to hours before the chemotherapy to avert side effects or hypersensitivity reactions (i.e. allergic reactions). [citation needed]