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This method is commonly offered by fertility clinics using donor sperm because the increased pregnancy rate results in fewer donor samples being used for the same number of pregnancies. Semen used for IUI must first be 'washed' to provide a pure sperm sample: this prevents 'cramping' following the insemination.
The first recorded case of artificial insemination was John Hunter in 1790, who helped impregnate a linen draper's wife. [1] [2] The first reported case of artificial insemination by donor occurred in 1884: William H. Pancoast, a professor in Philadelphia, took sperm from his "best looking" student to inseminate an anesthetized woman without her knowledge.
Semen supplied by a sperm bank prepared for ICI or IUI use is also suitable for ICI. A retrospective cohort study showed that total motility and total motile count (TMC) after thawing were associated with ongoing pregnancy rate; with best ICI results at total motility of ≥20% and a total motile count (TMC) of ≥8 × 106 after thawing. [39]
Total motile spermatozoa (TMS) [25] or total motile sperm count (TMSC) [26] is a combination of sperm count, motility and volume, measuring how many million sperm cells in an entire ejaculate are motile. Use of approximately 20 million sperm of motility grade c or d in ICI, and 5 million ones in IUI may be an approximate recommendation.
Hims reports that the respondents who used their phone more than 20 times per day had a 30% increased risk for lower sperm concentration and 21% increased risk for total sperm count to be below ...
Study results indicate that ART can affect both women and men's sexual health negatively. [ 24 ] Usage of assisted reproductive technology including ovarian stimulation and in vitro fertilization have been associated with an increased overall risk of childhood cancer in the offspring, which may be caused by the same original disease or ...
On the other hand, in women who have had previous unsuccessful treatment, IVF achieves a live birth rate approximately 2–3 times greater than ovarian stimulation combined with IUI. [ 8 ] IUI and ICI has higher pregnancy rates when combined with ovarian stimulation in couples with unexplained infertility, for IUI being 13% unstimulated and 15% ...
The World Health Organisation also adds that 'women whose pregnancy spontaneously miscarries, or whose pregnancy results in a still born child, without ever having had a live birth would present with primarily infertility'. [16] Secondary infertility is defined as the difficulty in conceiving a live birth in couples who previously had a child. [16]