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Apixaban, sold under the brand name Eliquis, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation through directly inhibiting factor Xa.
Doses of rivaroxaban under 10 mg can be taken with or without food, as it displayed high bioavailability independent of whether food was consumed or not. [38] If rivaroxaban is given at oral doses of 15 mg or 20 mg, it needs to be taken with food to aid in drug absorption and achieve appropriate bioavailability (≥ 80%).
100 mg Dihydrocodeine: 1 ⁄ 5: 50 mg 20% 4 Anileridine [16] 1 ⁄ 4: 40 mg Alphaprodine: 1 ⁄ 6: 40–60 mg Tapentadol [17] 3 ⁄ 10: 32 mg 32% (fasting) Pethidine (meperidine) 1 ⁄ 3: 30 mg SC/IV/IM. 300 mg 50–60% Orally, 100% SC/IV/IM: 3–5 5–15 sec if IV, 15–25 min if orally Dipipanone [18] [19] 2 ⁄ 5: 25 mg 3.2–3.8 hours ±4 ...
Catheter-directed thrombolysis with thrombectomy [141] against iliofemoral DVT has been associated with a reduction in the severity of post-thrombotic syndrome at an estimated cost-effectiveness ratio of about $138,000 [m] per gained QALY. [144] [145] Phlegmasia cerulea dolens might be treated with catheter-directed thrombolysis and/or ...
Atrial fibrillation (AF, AFib or A-fib) is an abnormal heart rhythm (arrhythmia) characterized by rapid and irregular beating of the atrial chambers of the heart. [11] [12] It often begins as short periods of abnormal beating, which become longer or continuous over time. [4]
The LD 50 for warfarin is 50–100 mg/kg for a single dose, after 5–7 days. [109] LD 50 1 mg/kg for repeated daily doses for 5 days, after 5–8 days. [109] The IDLH value is 100 mg/m 3 (warfarin; various species). [111] Resistance to warfarin as a poison has developed in many rat populations due to an autosomal dominant on chromosome 1 in ...
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