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Muscimol (also known as agarin or pantherine) is one of the principal psychoactive constituents of Amanita muscaria and related species of mushroom. Muscimol is a potent and selective orthosteric agonist for the GABA A receptor [3] and displays sedative-hypnotic, depressant and hallucinogenic [citation needed] psychoactivity.
[33]: 36–41, 52 Cultivated mushrooms have less variability in psilocybin content than wild mushrooms. [229] The drug is more stable in dried than fresh mushrooms; dried mushrooms retain their potency for months or even years, [33]: 51–5 while mushrooms stored fresh for four weeks contain only traces of the original psilocybin. [56]
Recreational doses of psilocybin mushrooms are typically between 1.0 to 3.5–5.0 g of dry mushrooms and 10 to 50 g of fresh mushrooms. [ 48 ] [ 51 ] This corresponds to a dosage of psilocybin of about 10 to 50 mg. [ 51 ] Usual doses of the common species P. cubensis range around 1.0 to 2.5 g, while about 2.5 to 5.0 g dried mushroom material is ...
A therapist and support person are there to help create a safe space and to listen or reassure during the trip, which lasts about five hours. “Patients are basically staying in one place for the ...
Psilocybe semilanceata, commonly known as the liberty cap, is a species of fungus which produces the psychoactive compounds psilocybin, psilocin and baeocystin.It is both one of the most widely distributed psilocybin mushrooms in nature, and one of the most potent.
Psilocybe azurescens is a species of psychedelic mushroom whose main active compounds are psilocybin and psilocin.It is among the most potent of the tryptamine-bearing mushrooms, containing up to 1.8% psilocybin, 0.5% psilocin, and 0.4% baeocystin by dry weight, averaging to about 1.1% psilocybin and 0.15% psilocin.
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