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The aorta (/ eɪ ˈ ɔːr t ə / ay-OR-tə; pl.: aortas or aortae) is the main and largest artery in the human body, originating from the left ventricle of the heart, branching upwards immediately after, and extending down to the abdomen, where it splits at the aortic bifurcation into two smaller arteries (the common iliac arteries).
The aortic valve is a valve in the heart of humans and most other animals, located between the left ventricle and the aorta. It is one of the four valves of the heart and one of the two semilunar valves , the other being the pulmonary valve .
The aortic root is the portion of the aorta beginning at the aortic annulus and extending to the sinotubular junction. It is sometimes regarded as a part of the ascending aorta, [ 2 ] and sometimes regarded as a separate entity from the rest of the ascending aorta.
Blood flows from the upper curvature to the upper regions of the body, located above the heart - namely the arms, neck, and head. Coming out of the heart, the thoracic aorta has a maximum diameter of 40 mm at the root. By the time it becomes the ascending aorta, the diameter should be < 35–38 mm, and 30 mm at the arch.
The two coronary arteries of the heart arise from the aortic root, just above the cusps of the aortic valve. The aorta then arches back over the right pulmonary artery. Three vessels come out of the aortic arch: the brachiocephalic artery, the left common carotid artery, and the left subclavian artery.
Coronary artery disease (CAD) or ischemic heart disease are the terms used to describe narrowing of the coronary arteries. [8] As the disease progresses, plaque buildup can partially block blood flow to the heart muscle. Without enough blood supply , the heart is unable to work properly, especially under increased stress.
The aortic and pulmonary valves are located at the base of the aorta and the pulmonary trunk respectively. These are also called the "semilunar valves". These two arteries receive blood from the ventricles and their semilunar valves permit blood to be forced into the arteries, and prevent backflow from the arteries into the ventricles.
Baroreceptors are stretch receptors located in the aortic sinus, carotid bodies, the venae cavae, and other locations, including pulmonary vessels and the right side of the heart itself. Baroreceptors fire at a rate determined by how much they are stretched, [ 52 ] which is influenced by blood pressure, level of physical activity, and the ...
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