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The most prominent side effects are dizziness and sleepiness. [41] Diphenhydramine is a potent anticholinergic agent and potential deliriant in higher doses. This activity is responsible for the side effects of dry mouth and throat, increased heart rate, pupil dilation, urinary retention, constipation, and, at high doses, hallucinations or ...
Diphenhydramine was the prototypical agent in this group. Significant anticholinergic adverse effects, as well as sedation, are observed in this group but the incidence of gastrointestinal adverse effects is relatively low. [4] [15] Diphenhydramine; Carbinoxamine; Doxylamine; Orphenadrine; Bromazine; Clemastine; Dimenhydrinate; Alkylamines
Benadryl containing diphenhydramine can interact with alcohol as both are central nervous system (CNS) depressants. Side effects such as drowsiness and dizziness may be enhanced when taking alcohol with diphenhydramine. [16] Mixing diphenhydramine with alcohol can also increase the chances of losing consciousness due to sedation. [17]
But antihistamines like promethazine, doxylamine, and diphenhydramine can interfere with your body temperature regulation and tamp down on your ability to sweat, according to the CDC. Stimulants
Diphenhydramine hydrochloride is also marketed as an antihistamine in Canada under the same name, and is only listed in the Canadian Agricultural database for equine use. [5] However, a 2019 manual for counseling professionals in Canada included Sominex as a medicine to be used for the treatment of Parkinson's tremors and stiffness related to ...
Common side effects of dimenhydrinate may include drowsiness, dry mouth, nose, or throat, constipation, and blurred vision. Some individuals, particularly children, may experience feelings of restlessness or excitement. In certain cases, more severe symptoms may arise, such as delirium, weakness, and a tendency to be easily startled.
Phenylephrine ‘is extensively broken down in the liver, resulting in little to no pharmacological effect’
Hydroxyzine works by blocking the effects of histamine. [9] It is a first-generation antihistamine in the piperazine family of chemicals. [8] [4] Common side effects include sleepiness, headache, and dry mouth. [8] [9] Serious side effects may include QT prolongation. [9] It is unclear if use during pregnancy or breastfeeding is safe. [8]
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